Deuterium with fractionator: MEDIUM LATE -> LATE GAME
This is a complete blueprint based on FauxPas "Efficient UPS Optimized Deuterium Fractionatior Tile".
I've compressed it with 1 tower and 2 sides. Prolifirated Hydrogen. Pilers are used on both sides to compress output. Power: Approximately 9.9MW per Fractionator = 356~MW while at full capacity. This requires a huge amount of Hydrogen, so make sure you have a gas giant nearby and preferably some local production.
Note: I have not made any calculations on what the actual output is, but a tile of 4 fractionators process 7200~ hydrogen per minute and theres 36 fractionators + prolifiration. Plop a few of these down and it will satisfy your deuterium needs for a good while.
All credit goes to FauxPas for designing the initial model.